Journal: Heliyon

Article Title: Antihyperglycemic activity of a novel polyherbal formula (HF344), a mixture of fifteen herb extracts, for the management of type 2 diabetes: Evidence from in vitro, ex vivo, and in vivo studies

doi: 10.1016/j.heliyon.2024.e38703

Figure Lengend Snippet: Effect of HF344 extract on cell viability (A) and insulin secretion in the rat insulinoma cell line RINm5F (B). Data are expressed as the mean ± SD (n = 3). ∗ , ∗∗p < 0.05 and p < 0.01 vs. control, respectively; Gli: glibenclamide; HF: HF344.

Article Snippet: The rat insulinoma cell line RINm5F (CRL-2058TM, passage number 19–24), obtained from American Type Culture Collection (ATCC®) was seeded at a density of 1x10 5 cells/mL.

Techniques: Control

Journal: Heliyon

Article Title: Antihyperglycemic activity of a novel polyherbal formula (HF344), a mixture of fifteen herb extracts, for the management of type 2 diabetes: Evidence from in vitro, ex vivo, and in vivo studies

doi: 10.1016/j.heliyon.2024.e38703

Figure Lengend Snippet: Effects of HF344 extract on the cell viability of the STZ-treated RINm5F cells, assessed using the MTT assay. In the "protective" condition (A), cell viability was evaluated after incubation with HF344 extract (1, 10, and 100 μg/mL) for 1 h before the addition of 6 mM STZ. In the "recovery" condition (B), cell viability was assessed after the addition of 6 mM STZ followed by incubation with HF344 extract (1, 10, and 100 μg/mL). Data are expressed as the mean ± SD (n = 4), #p < 0.05 vs control; ∗p < 0.05 vs STZ-treated cells, STZ, streptozotocin; HF: HF344.

Article Snippet: The rat insulinoma cell line RINm5F (CRL-2058TM, passage number 19–24), obtained from American Type Culture Collection (ATCC®) was seeded at a density of 1x10 5 cells/mL.

Techniques: MTT Assay, Incubation, Control